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Article

Improved clinical outcomes of preimplantation genetic testing for aneuploidy using MALBAC-NGS compared with MDA-SNP array.

BMC pregnancy and childbirth - 3 Jul 2020

Niu Wenbin, Wang Linlin, Xu Jiawei, Li Ying, Shi Hao, Li Gang, Jin Haixia, Song Wenyan, Wang Fang, Sun Yingpu

Abstract excerpt

BACKGROUND: To assess whether preimplantation genetic testing for aneuploidy with next generation sequencing (NGS) outweighs single nucleotide polymorphism (SNP) array in improving clinical outcomes. METHODS: A retrospective analysis of the clinical outcomes of patients who underwent PGT-A treatment in a single center from January 2013 to December 2017.A total of 1418 couples who underwent PGT-A treatment were...

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Identifiers

PMID: 32620095
DOI: 10.1186/s12884-020-03082-9
PMCID: PMC7333433

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