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Pre‐implantation genetic testing: Past, present, future

13 Oct 2020

Abstract excerpt

BACKGROUND: Pre-implantation genetic testing (PGT) has been performed worldwide since it was first used by Handyside et al in the United Kingdom to sex embryos in 1990. Until about 2010, cleavage stage embryo biopsy and fluorescent in situ hybridization (FISH) were mainstream; however, in 2012, blastocyst biopsy (trophectoderm; TE biopsy) became mainstream. In addition, array comparative genomic hybridization...

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PMID: 33488281
DOI: 10.1002/rmb2.12352

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