Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical application of embryo aneuploidy testing by next-generation sequencing

4 Feb 2019

Abstract excerpt

We review here the evolution in the field of embryo aneuploidy testing over the last 20 years, from the analysis of a subset of chromosomes by fluorescence in situ hybridisation to the transition toward a more comprehensive analysis of all 24 chromosomes. This current comprehensive aneuploidy testing most commonly employs next-generation sequencing (NGS). We present our experience in over 130 000 embryo biopsies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fetal and Pediatric Neurological Disorders
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30721942
DOI: 10.1093/biolre/ioz019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical application of embryo aneuploidy testing by next-generation sequencingPMID 30721942Read ↗

Application of next-generation sequencing for 24-chromosome aneuploidy screening of human preimplantation embryosSemantic proximity Read ↗

Preimplantation Genetic Testing for AneuploidySemantic proximity Read ↗

Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cyclesSemantic proximity Read ↗

Characteristics of the IVF Cycle that Contribute to the Incidence of MosaicismSemantic proximity Read ↗

Evaluation of the Effectiveness and Accuracy of Non-Invasive Preimplantation Genetic Testing (niPGT) Compared to Invasive Embryo BiopsySemantic proximity Read ↗

Preclinical validation of a targeted next generation sequencing-based comprehensive chromosome screening methodology in human blastocystsSemantic proximity Read ↗

Advancements and Challenges in Preimplantation Genetic Testing for Aneuploidies: In the Pathway to Non-Invasive TechniquesSemantic proximity Read ↗

Non-invasive preimplantation genetic testing for aneuploidy: is the promise real?Semantic proximity Read ↗

Pre-implantation genetic testing in ART: who will benefit and what is the evidence?Semantic proximity Read ↗

Challenges facing contemporary preimplantation genetic screening.Semantic proximity Read ↗

Extended in vitro culture of human embryos demonstrates the complex nature of diagnosing chromosomal mosaicism from a single trophectoderm biopsySemantic proximity Read ↗

Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.