Viral miRNAs in plasma and urine divulge JC polyomavirus infection

Abstract excerpt

BACKGROUND: JC polyomavirus (JCPyV) is a widespread human polyomavirus that usually resides latently in its host, but can be reactivated under immune-compromised conditions potentially causing Progressive Multifocal Leukoencephalopathy (PML). JCPyV encodes its own microRNA, jcv-miR-J1. METHODS: We have investigated in 50 healthy subjects whether jcv-miR-J1-5p (and its variant jcv-miR-J1a-5p) can be detected in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Energy Harvesting in Wireless Networks
• Share to Polyomavirus and related diseases
• Share to Viral-associated cancers and disorders