Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cocktail of H5N1 COBRA HA vaccines elicit protective antibodies against H5N1 viruses from multiple clades

4 Mar 2015

Abstract excerpt

Pandemic outbreaks of influenza are caused by the emergence of a pathogenic and transmissible virus to which the human population is immunologically naïve. Recent outbreaks of highly pathogenic avian influenza (HPAI) of the H5N1 subtype are of particular concern because of the high mortality rate (60% case fatality rate) and novel subtype. In this study, we have engineered an influenza virus-like particle (VLP)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Influenza Virus Research Studies
Share to Respiratory viral infections research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25671661
DOI: 10.1080/21645515.2015.1012013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cocktail of H5N1 COBRA HA vaccines elicit protective antibodies against H5N1 viruses from multiple cladesPMID 25671661Read ↗

A Computationally Optimized Hemagglutinin Virus-Like Particle Vaccine Elicits Broadly Reactive Antibodies that Protect Nonhuman Primates from H5N1 InfectionSemantic proximity Read ↗

A Single Dose of Inactivated Influenza Virus Vaccine Expressing COBRA Hemagglutinin Elicits Broadly-Reactive and Long-Lasting ProtectionSemantic proximity Read ↗

The pre-existing human antibody repertoire to computationally optimized influenza H1 hemagglutinin vaccinesSemantic proximity Read ↗

Elicitation of protective immune responses using a bivalent H5N1 VLP vaccineSemantic proximity Read ↗

Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccineSemantic proximity Read ↗

A VLP Vaccine Induces Broad-Spectrum Cross-Protective Antibody Immunity against H5N1 and H1N1 Subtypes of Influenza A VirusSemantic proximity Read ↗

Immunoinformatics-Guided Design and In Silico Evaluation of a Multi-Epitope Vaccine Against Influenza A H10N5 and H3N2 Strains Based on Hemagglutinin and Neuraminidase ProteinsSemantic proximity Read ↗

Polyvalent DNA Vaccines Expressing HA Antigens of H5N1 Influenza Viruses with an Optimized Leader Sequence Elicit Cross-Protective Antibody ResponsesSemantic proximity Read ↗

H5N1 Virus-Like Particle Vaccine Elicits Cross-Reactive Neutralizing Antibodies That Preferentially Bind to the Oligomeric Form of Influenza Virus Hemagglutinin in HumansSemantic proximity Read ↗

A Triclade DNA Vaccine Designed on the Basis of a Comprehensive Serologic Study Elicits Neutralizing Antibody Responses against All Clades and Subclades of Highly Pathogenic Avian Influenza H5N1 VirusesSemantic proximity Read ↗

Feasibility of reconstructed ancestral H5N1 influenza viruses for cross-clade protective vaccine developmentSemantic proximity Read ↗

A broad-spectrum vaccine candidate against H5 viruses bearing different sub-clade 2.3.4.4 HA genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.