Article

Immunoinformatics-Guided Design and In Silico Evaluation of a Multi-Epitope Vaccine Against Influenza A H10N5 and H3N2 Strains Based on Hemagglutinin and Neuraminidase Proteins

2026-07-08

Abstract excerpt

Influenza A viruses H3N2 and H10N5 represent, respectively, a persistently dominant seasonal pathogen and a newly documented zoonotic threat with the latter strain variants responsible for the first confirmed human fatality in January 2024, yet no vaccine platform currently addresses co-protection against both subtypes within a unified immunogen. We report here the immunoinformatics based vaccine design and multi-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1546b4aa-cb35-5eda-996e-a43eada374d3
DOI: 10.64898/2026.07.03.736294

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Immunoinformatics-Guided Design and In Silico Evaluation of a Multi-Epitope Vaccine Against Influenza A H10N5 and H3N2 Strains Based on Hemagglutinin and Neuraminidase ProteinsDOI 10.64898/2026.07.03.736294Read

An AI-Driven Framework for the Design and Development of the Next-Generation Avian Viral VaccinesSemantic proximity Read

In silico design of recombinant multi-epitope vaccine against influenza A virusSemantic proximity Read

Immunoinformatics-aided rational design of multiepitope-based peptide vaccine (MEBV) targeting human parainfluenza virus 3 (HPIV-3) stable proteinsSemantic proximity Read

Targeting H3N2 Influenza: Advancements in Treatment and Vaccine StrategiesSemantic proximity Read

Beyond the state of the art of reverse vaccinology: predicting vaccine efficacy with the universal immune system simulator for influenzaSemantic proximity Read

Structure-aware deep learning predicts influenza antigenicity and guides vaccine strain recommendationSemantic proximity Read

Reverse vaccinology approach to design a novel multi-epitope subunit vaccine against avian influenza A (H7N9) virusSemantic proximity Read

Beyond the state of the art of reverse vaccinology: predicting vaccine efficacy with the Universal Immune System Simulator for influenzaSemantic proximity Read

Robust Multiepitope Vaccine from Glycoproteins Against Human Metapneumovirus Genotypes A2a, A2b, and A2c by Utilizing Immunoinformatics and Reverse Vaccinology ApproachesSemantic proximity Read

An Immunoinformatics Prediction of Novel Multi-Epitope Vaccines Candidate Against Surface Antigens of Nipah VirusSemantic proximity Read

The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017Semantic proximity Read

Potent efficacy of a NA-targeting antibody against a broad spectrum of H5N1 influenza virusesSemantic proximity Read