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Article

Patterns of metabolite changes identified from large-scale gene perturbations in Arabidopsis using a genome-scale metabolic network.

Plant physiology - 1 Apr 2015

Kim Taehyong, Dreher Kate, Nilo-Poyanco Ricardo, Lee Insuk, Fiehn Oliver, Lange Bernd Markus, Nikolau Basil J, Sumner Lloyd, Welti Ruth, Wurtele Eve S, Rhee Seung Y

Abstract excerpt

Metabolomics enables quantitative evaluation of metabolic changes caused by genetic or environmental perturbations. However, little is known about how perturbing a single gene changes the metabolic system as a whole and which network and functional properties are involved in this response. To answer this question, we investigated the metabolite profiles from 136 mutants with single gene perturbations of...

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Identifiers

PMID: 25670818
DOI: 10.1104/pp.114.252361
PMCID: PMC4378150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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