Article
New connections across pathways and cellular processes: industrialized mutant screening reveals novel associations between diverse phenotypes in Arabidopsis.
Plant physiology - 1 Apr 2008
Lu Yan, Savage Linda J, Ajjawi Imad, Imre Kathleen M, Yoder David W, Benning Christoph, Dellapenna Dean, Ohlrogge John B, Osteryoung Katherine W, Weber Andreas P, Wilkerson Curtis G, Last Robert L
Abstract excerpt
In traditional mutant screening approaches, genetic variants are tested for one or a small number of phenotypes. Once bona fide variants are identified, they are typically subjected to a limited number of secondary phenotypic screens. Although this approach is excellent at finding genes involved in specific biological processes, the lack of wide and systematic interrogation of phenotype limits the ability to...
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