Article
Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana.
BMC systems biology - 21 Nov 2007
Kusano Miyako, Fukushima Atsushi, Arita Masanori, Jonsson Pär, Moritz Thomas, Kobayashi Makoto, Hayashi Naomi, Tohge Takayuki, Saito Kazuki
Abstract excerpt
BACKGROUND: Metabolites are not only the catalytic products of enzymatic reactions but also the active regulators or the ultimate phenotype of metabolic homeostasis in highly complex cellular processes. The modes of regulation at the metabolome level can be revealed by metabolic networks. We investigated the metabolic network between wild-type and 2 mutant (methionine-over accumulation 1 [mto1] and transparent...
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