Article
Pathogenomics of mobile genetic elements of toxigenic bacteria.
International journal of medical microbiology : IJMM - 1 Apr 2004
Hacker Jörg, Hochhut Bianca, Middendorf Barbara, Schneider György, Buchrieser Carmen, Gottschalk Gerhard, Dobrindt Ulrich
Abstract excerpt
The growing knowledge of genetic diversity and whole genome organization in bacteria shows that pathogenicity islands (PAIs) represent a subtype of a more general genetic element, termed genomic island (GEI), which is widespread among pathogenic and non-pathogenic microbes. These findings mirror the importance of horizontal gene transfer, genome reduction and recombination events as fundamental mechanisms...
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