Article
FUN-L: gene prioritization for RNAi screens.
Bioinformatics (Oxford, England) - 15 Jun 2015
Lees Jonathan G, Hériché Jean-Karim, Morilla Ian, Fernández José M, Adler Priit, Krallinger Martin, Vilo Jaak, Valencia Alfonso, Ellenberg Jan, Ranea Juan A, Orengo Christine
Abstract excerpt
MOTIVATION: Most biological processes remain only partially characterized with many components still to be identified. Given that a whole genome can usually not be tested in a functional assay, identifying the genes most likely to be of interest is of critical importance to avoid wasting resources. RESULTS: Given a set of known functionally related genes and using a state-of-the-art approach to data integration...
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