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Article

Autophagy in Helicobacter pylori Infection and Related Gastric Cancer.

Helicobacter - 1 Oct 2015

Castaño-Rodríguez Natalia, Kaakoush Nadeem O, Goh Khean-Lee, Fock Kwong Ming, Mitchell Hazel M

Abstract excerpt

BACKGROUND: Autophagy, a degradation pathway in which cytoplasmic content is engulfed and degraded by lysosomal hydrolases, plays a pivotal role in infection and inflammation. Given that defects in autophagy lead to increased susceptibility to infection, we investigated the role of autophagy in Helicobacter pylori-related gastric cancer (GC). MATERIALS AND METHODS: Gene expression of 84 molecules was examined...

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Source

Identifiers

PMID: 25664588
DOI: 10.1111/hel.12211

Genes

IRGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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