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Article

Up-regulation of Kv1.3 channels by janus kinase 2.

The Journal of membrane biology - 1 Apr 2015

Hosseinzadeh Zohreh, Warsi Jamshed, Elvira Bernat, Almilaji Ahmad, Shumilina Ekaterina, Lang Florian

Abstract excerpt

The janus-activated kinase 2 JAK2 participates in the signalling of several hormones including interferon, a powerful regulator of lymphocyte function. Lymphocyte activity and survival depend on the activity of the voltage-gated K(+) channel KCNA3 (Kv1.3). The present study thus explored whether JAK2 modifies the activity of voltage-gated K(+) channel KCNA3. To this end, cRNA encoding KCNA3 was injected in...

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Source

Identifiers

PMID: 25644777
DOI: 10.1007/s00232-015-9772-2

Genes

JAK2
KCNA3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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