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Article

Ca2+-Activated K+ Channel KCa3.1 as a Therapeutic Target for Immune Disorders.

Biological & pharmaceutical bulletin - 1 Jan 2018

Ohya Susumu, Kito Hiroaki

Abstract excerpt

In lymphoid and myeloid cells, membrane hyperpolarization by the opening of K+ channels increases the activity of Ca2+ release-activated Ca2+ (CRAC) channels and transient receptor potential (TRP) Ca2+ channels. The intermediate-conductance Ca2+-activated K+ channel KCa3.1 plays an important role in cell proliferation, differentiation, migration, and cytokine production in innate and adaptive immune systems....

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Identifiers

PMID: 30068864
DOI: 10.1248/bpb.b18-00078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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