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Article

Next-generation gene discovery for variants of large impact on lipid traits.

Current opinion in lipidology - 1 Apr 2015

Rosenthal Elisabeth, Blue Elizabeth, Jarvik Gail P

Abstract excerpt

PURPOSE OF REVIEW: Detection of high-impact variants on lipid traits is complicated by complex genetic architecture. Although genome-wide association studies (GWAS) successfully identified many novel genes associated with lipid traits, it was less successful in identifying variants with a large impact on the phenotype. This is not unexpected, as the more common variants detectable by GWAS typically have small...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25636063
DOI: 10.1097/MOL.0000000000000156
PMCID: PMC4388051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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