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Article

Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon

31 Jul 2014

Abstract excerpt

BACKGROUND: Burkholderia pseudomallei is a facultative intracellular pathogen and the causative agent of melioidosis. A conserved type III secretion system (T3SS3) and type VI secretion system (T6SS1) are critical for intracellular survival and growth. The T3SS3 and T6SS1 genes are coordinately and hierarchically regulated by a TetR-type regulator, BspR. A central transcriptional regulator of the BspR regulatory...

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PMID: 25085508
DOI: 10.1186/s12866-014-0206-6

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