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Adaptation of red blood cell lysis represents a fundamental breakthrough that improves the sensitivity of <i> <scp>S</scp> almonella </i> detection in blood

29 Jan 2015

Abstract excerpt

AIMS: Isolation of Salmonella Typhi from blood culture is the standard diagnostic for confirming typhoid fever but it is unavailable in many developing countries. We previously described a Microwave Accelerated Metal Enhanced Fluorescence (MAMEF)-based assay to detect Salmonella in medium. Attempts to detect Salmonella in blood were unsuccessful, presumably due to the interference of erythrocytes. The objective...

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PMID: 25630831
DOI: 10.1111/jam.12769

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