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Article

Determining genotype and antimicrobial resistance of Salmonella Typhi in environmental samples by amplicon sequencing.

PLoS neglected tropical diseases - 1 Jul 2025

Troman Catherine, Horsfield Samuel T, Abraham Dilip, Mohan Venkata Raghava, Giri Sidhartha, Nair Satheesh, Shaw Alexander G, Dyson Zoe, Holt Kathryn E, Grassly Nicholas C

Abstract excerpt

BACKGROUND: Estimates of the burden of typhoid fever due to Salmonella enterica serovar Typhi (S. Typhi) rely on data from clinical surveillance, which is rarely done in low income settings and is also limited by the poor sensitivity of the assays used and the reliance on health seeking by patients. Environmental surveillance for S. Typhi shed by symptomatic and asymptomatic individuals in wastewater offers a...

Read the complete abstract on PubMed

Topics

Salmonella typhi
Genotype
Wastewater
Humans
Typhoid Fever
Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Anti-Bacterial Agents

India

Sequence Analysis, DNA

Microbial Sensitivity Tests

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 40627640
DOI: 10.1371/journal.pntd.0013211
PMCID: PMC12237024

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