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Article

Opposite Roles of BAP1 in Overall Survival of Uveal Melanoma and Cutaneous Melanoma

3 Feb 2020

Abstract excerpt

BACKGROUND: BRCA1-Associated Protein 1 (BAP1) germline mutations predispose individuals to cancers, including uveal melanoma (UM) and cutaneous melanoma (CM). BAP1 loss is common in UM and is associated with a worse prognosis. BAP1 loss is rare in CM and the outcome is unclear. METHODS: UM and CM data was retrieved from The Cancer Genome Atlas (TCGA) database. Cox regression model was performed to examine whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32028647
DOI: 10.3390/jcm9020411

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