Article
Echocardiographic speckle-tracking based strain imaging for rapid cardiovascular phenotyping in mice.
Circulation research - 15 Apr 2011
Bauer Michael, Cheng Susan, Jain Mohit, Ngoy Soeun, Theodoropoulos Catherine, Trujillo Anna, Lin Fen-Chiung, Liao Ronglih
Abstract excerpt
RATIONALE: High-sensitivity in vivo phenotyping of cardiac function is essential for evaluating genes of interest and novel therapies in small animal models of cardiovascular disease. Transthoracic echocardiography is the principal method currently used for assessing cardiac structure and function; however, standard echocardiographic techniques are relatively insensitive to early or subtle changes in cardiac...
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