Article
Mechanotransduction mechanisms for intraventricular diastolic vortex forces and myocardial deformations: part 1.
Journal of cardiovascular translational research - 1 Feb 2015
Pasipoularides Ares
Abstract excerpt
Epigenetic mechanisms are fundamental in cardiac adaptations, remodeling, reverse remodeling, and disease. This two-article series proposes that variable forces associated with diastolic RV/LV rotatory intraventricular flows can exert physiologically and clinically important, albeit still unappreciated, epigenetic actions influencing functional and morphological cardiac adaptations and/or maladaptations. Taken in...
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