Article
Archival bone marrow samples: suitable for multiple biomarker analysis.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2015
Lund Bendik, Najmi Laeya A, Wesolowska-Andersen Agata, Landsem Veslemøy M, Rasmussen Kirsten K, Borst Louise, Gupta Ramneek, Schmiegelow Kjeld, Klungland Helge
Abstract excerpt
AB Archival samples represent a significant potential for genetic studies, particularly in severe diseases with risk of lethal outcome, such as in cancer. In this pilot study, we aimed to evaluate the usability of archival bone marrow smears and biopsies for DNA extraction and purification, whole genome amplification (WGA), multiple marker analysis including 10 short tandem repeats, and finally a comprehensive...
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