Closing the translational gap between mutant mouse models and the clinical reality of psychotic illness.

Abstract excerpt

As animal models of psychotic illness become more refined, mutant mouse models have become increasingly prominent through their ability to inform on the structural, cellular and behavioural roles of genes associated with risk for psychosis via the phenotypic consequences of disruption of those genes. This review will consider recent advances in the field whereby mutant mouse models seek to reflect increasing...

Topics

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• Disease Models, Animal
• Gene-Environment Interaction
• Mice
• Mice, Transgenic
• Mutation