Article
Genetic models of schizophrenia and related psychotic disorders: progress and pitfalls across the methodological "minefield".
Cell and tissue research - 1 Oct 2013
O'Tuathaigh Colm M P, Moran Paula M, Waddington John L
Abstract excerpt
The challenge of modelling a complex and multifaceted disorder such as schizophrenia is epitomised by the considerable degree of phenotypic variability described in patients and by the absence of specific and consistent neuropathological biomarkers. The pattern and severity of a range of clinical features, including florid psychotic symptoms such as hallucinations and delusions, negative symptoms and cognitive...
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