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Article

Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma.

Journal of virology - 15 Jan 2018

Borozan Ivan, Zapatka Marc, Frappier Lori, Ferretti Vincent

Abstract excerpt

Epstein-Barr virus (EBV) is a causative agent of a variety of lymphomas, nasopharyngeal carcinoma (NPC), and ∼9% of gastric carcinomas (GCs). An important question is whether particular EBV variants are more oncogenic than others, but conclusions are currently hampered by the lack of sequenced EBV genomes. Here, we contribute to this question by mining whole-genome sequences of 201 GCs to identify 13 EBV-positive...

Topics

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Adenocarcinoma
Epitopes, T-Lymphocyte
Epstein-Barr Virus Infections
Gene Expression Regulation, Viral
Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Herpesvirus 4, Human

Stomach Neoplasms

Whole Genome Sequencing

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Identifiers

PMID: 29093097
DOI: 10.1128/JVI.01239-17
PMCID: PMC5752941

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