Article
Do genes modify the association of selenium and lipid levels?
Antioxidants & redox signaling - 20 May 2015
Galan-Chilet Inmaculada, Guallar Eliseo, Martin-Escudero J Carlos, De Marco Griselda, Dominguez-Lucas Alejandro, Gonzalez-Manzano Isabel, Lopez-Izquierdo Raul, Redon Josep, Chaves F Javier, Tellez-Plaza Maria
Abstract excerpt
The interaction of selenium, a component of antioxidant selenoproteins, with genetic variation in lipid-related pathways has not been evaluated earlier as a potential determinant of blood lipid levels. We aimed at evaluating the effects of gene-environment interactions between plasma levels of selenium and polymorphisms in lipid metabolic pathways on plasma lipid levels in a study population from Spain (N=1,315)....
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