Article
Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors.
Lipids in health and disease - 30 Apr 2018
Shatwan Israa M, Winther Kristian Hillert, Ellahi Basma, Elwood Peter, Ben-Shlomo Yoav, Givens Ian, Rayman Margaret P, Lovegrove Julie A, Vimaleswaran Karani S
Abstract excerpt
BACKGROUND: Several candidate genes have been identified in relation to lipid metabolism, and among these, lipoprotein lipase (LPL) and apolipoprotein E (APOE) gene polymorphisms are major sources of genetically determined variation in lipid concentrations. This study investigated the association of two single nucleotide polymorphisms (SNPs) at LPL, seven tagging SNPs at the APOE gene, and a common APOE haplotype...
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