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Article

Podocyte dysfunction in atypical haemolytic uraemic syndrome.

Nature reviews. Nephrology - 1 Apr 2015

Noris Marina, Mele Caterina, Remuzzi Giuseppe

Abstract excerpt

Genetic or autoimmune defects that lead to dysregulation of the alternative pathway of complement have been associated with the development of atypical haemolytic uraemic syndrome (aHUS), which is characterized by thrombocytopenia, haemolytic anaemia and acute kidney injury. The relationship between aHUS, podocyte dysfunction and the resultant proteinuria has not been adequately investigated. However, the report...

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Identifiers

PMID: 25599621
DOI: 10.1038/nrneph.2014.250

Genes

DGKE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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