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Article

Clonal and constricted T cell repertoire in Common Variable Immune Deficiency.

Clinical immunology (Orlando, Fla.) - 1 May 2017

Ramesh Manish, Hamm David, Simchoni Noa, Cunningham-Rundles Charlotte

Abstract excerpt

We used high throughput sequencing to examine the structure and composition of the T cell receptor β chain in Common Variable Immune Deficiency (CVID). TCRβ CDR3 regions were amplified and sequenced from genomic DNA of 44 adult CVID subjects and 22 healthy adults, using a high-throughput multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25596453
DOI: 10.1016/j.clim.2015.01.002
PMCID: PMC4501913

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25596453-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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