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Article

Maternal high-fat diet exaggerates atherosclerosis in adult offspring by augmenting periaortic adipose tissue-specific proinflammatory response.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2015

Wakana Noriyuki, Irie Daisuke, Kikai Masakazu, Terada Kensuke, Yamamoto Keita, Kawahito Hiroyuki, Kato Taku, Ogata Takehiro, Ueyama Tomomi, Matoba Satoaki, Yamada Hiroyuki

Abstract excerpt

OBJECTIVE: Maternal obesity elicits offspring's metabolic disorders via developmental modifications of visceral adipose tissue; however, its effect on atherogenesis remains undefined. Perivascular adipose tissue has recently been implicated in vascular remodeling and vasoreactivity. We hypothesize that developmental modifications of perivascular adipose tissue by maternal high-fat diet (HFD) exposure promotes...

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Source

Identifiers

PMID: 25593133
DOI: 10.1161/ATVBAHA.114.305122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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