Article
Measures of exposure impact genetic association studies: an example in vitamin K levels and VKORC1.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2015
Crawford Dana C, Brown-Gentry Kristin, Rieder Mark J
Abstract excerpt
Studies assessing the impact of gene-environment interactions on common human diseases and traits have been relatively few for many reasons. One often acknowledged reason is that it is difficult to accurately measure the environment or exposure. Indeed, most large-scale epidemiologic studies use questionnaires to assess and measure past and current exposure levels. While questionnaires may be cost-effective, the...
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