Article
Nutri-pharmacogenomics of warfarin anticoagulation therapy: VKORC1 genotype-dependent influence of dietary vitamin K intake.
Journal of thrombosis and thrombolysis - 1 Jul 2014
Saito Ryuhei, Takeda Kenji, Yamamoto Kayo, Nakagawa Akihiko, Aoki Hirofumi, Fujibayashi Kosuke, Wakasa Minoru, Motoyama Atsushi, Iwadare Mizuho, Ishida Ryoko, Fujioka Nakaba, Tsuchiya Taketsugu, Akao Hironobu, Kawai Yasuyuki, Kitayama Michihiko, Kajinami Kouji
Abstract excerpt
Warfarin is the most widely prescribed oral anticoagulant, but large interindividual variations exist in the dose required to achieve comparable therapeutic effects. Several clinical and genetic variables have been identified that influence warfarin dosing. However, interactions between genotype...
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