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Article

The OPN gene polymorphism confers the susceptibility and response to Ara-C based chemotherapy in Chinese AML patients.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2015

Zhang Rong, Yang Wei, Li Ying Chun, Zhang Guo Jun, Yao Kun, Hu Rong, Wu Bin

Abstract excerpt

AIM: To investigate the possible association between the Osteopontin (OPN) gene polymorphisms and the susceptibility and chemotherapy response of acute myeloid leukemia patients. METHODS: A total of 381 patients with de nova AML and 430 healthy controls were enrolled. All patients received Ara-C-based standard induction chemotherapy regimens, and the treatment response was evaluated. Several polymorphisms in the...

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PMID: 25591760
DOI: 10.1159/000369685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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