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PCDH10, a novel p53 transcriptional target in regulating cell migration

19 Mar 2015

Abstract excerpt

Cell cycle arrest, senescence and apoptosis are commonly regarded as the major tumor suppression mechanisms of p53. However, accumulating evidence indicates that loss of these canonical functions is not sufficient for tumor formation, highlighting the complexity of p53-mediated tumor suppression. PCDH10 belongs to a proto cadherin protein family and is a potential tumor suppressor protein as the dysregulation of...

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PMID: 25590240
DOI: 10.1080/15384101.2015.1004935

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