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Article

Signaling pathway activation drift during aging: Hutchinson-Gilford Progeria Syndrome fibroblasts are comparable to normal middle-age and old-age cells.

Aging - 1 Jan 2015

Aliper Alexander M, Csoka Antonei Benjamin, Buzdin Anton, Jetka Tomasz, Roumiantsev Sergey, Moskalev Alexy, Zhavoronkov Alex

Abstract excerpt

For the past several decades, research in understanding the molecular basis of human aging has progressed significantly with the analysis of premature aging syndromes. Progerin, an altered form of lamin A, has been identified as the cause of premature aging in Hutchinson-Gilford Progeria Syndrome...

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Identifiers

PMID: 25587796
DOI: 10.18632/aging.100717
PMCID: PMC4350323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25587796-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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