Article
Meta-analysis of the relationship between ACE I/D gene polymorphism and end-stage renal disease in patients with diabetic nephropathy.
Nephrology (Carlton, Vic.) - 1 Jul 2012
Yu Ze-Yan, Chen Li-Sheng, Zhang Lei-Chang, Zhou Tian-Biao
Abstract excerpt
AIMS: Diabetic nephropathy (DN) is the major cause for end-stage renal disease (ESRD) and the pathogenesis for DN developing into ESRD is not clear at present. Results from published studies on the relationship between angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism and ESRD risk in DN patients are still conflicting. This meta-analysis was performed to evaluate the association...
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