Article
Host genetic susceptibility, dysbiosis, and viral triggers in inflammatory bowel disease.
Current opinion in gastroenterology - 1 Jul 2011
Sun Lulu, Nava Gerardo M, Stappenbeck Thaddeus S
Abstract excerpt
PURPOSE OF REVIEW: Inflammatory bowel disease (IBD) is thought to occur in genetically susceptible individuals. However, environmental factors, potentially including shifts in commensal microbiota, are also required to trigger disease. This review discusses some of the recent discoveries in host susceptibility and interaction with the microbial environment, and pinpoints key areas for advancement in our...
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