Pseudoangiomatous stromal hyperplasia with multinucleated stromal giant cells is neither exceptional in gynecomastia nor characteristic of neurofibromatosis type 1.

doi:10.1007/s00428-014-1715-2

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Article

Pseudoangiomatous stromal hyperplasia with multinucleated stromal giant cells is neither exceptional in gynecomastia nor characteristic of neurofibromatosis type 1.

Virchows Archiv : an international journal of pathology - 1 Apr 2015

Pižem Jože, Velikonja Mojca, Matjašič Alenka, Jerše Maja, Glavač Damjan

Abstract excerpt

Six cases of gynecomastia with pseudoangiomatous stromal hyperplasia (PASH) and multinucleated stromal giant cells (MSGC) associated with neurofibromatosis type 1 (NF1) have been reported, and finding MSGC within PASH in gynecomastia has been suggested as being a characteristic of NF1. The frequency of PASH with MSGC in gynecomastia and its specificity for NF1 have not, however, been systematically studied. A...

Topics

Adolescent
Adult
Aged
Angiomatosis
Breast Diseases
Child
Genes, Neurofibromatosis 1
Giant Cells
Gynecomastia
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hyperplasia

Male

Middle Aged

Mutation

Neurofibromatosis 1

Young Adult

Source

Open in PubMed

Identifiers

PMID: 25586494
DOI: 10.1007/s00428-014-1715-2

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