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Article

Sparse expression bases in cancer reveal tumor drivers.

Nucleic acids research - 18 Feb 2015

Logsdon Benjamin A, Gentles Andrew J, Miller Chris P, Blau C Anthony, Becker Pamela S, Lee Su-In

Abstract excerpt

We define a new category of candidate tumor drivers in cancer genome evolution: 'selected expression regulators' (SERs)-genes driving dysregulated transcriptional programs in cancer evolution. The SERs are identified from genome-wide tumor expression data with a novel method, namely SPARROW ( SPAR: se selected exp R: essi O: n regulators identified W: ith penalized regression). SPARROW uncovers a previously...

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PMID: 25583238
DOI: 10.1093/nar/gku1290
PMCID: PMC4330344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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