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Article

Recognition determinants of broadly neutralizing human antibodies against dengue viruses.

Nature - 2 Apr 2015

Rouvinski Alexander, Guardado-Calvo Pablo, Barba-Spaeth Giovanna, Duquerroy Stéphane, Vaney Marie-Christine, Kikuti Carlos M, Navarro Sanchez M Erika, Dejnirattisai Wanwisa, Wongwiwat Wiyada, Haouz Ahmed, Girard-Blanc Christine, Petres Stéphane, Shepard William E, Desprès Philippe, Arenzana-Seisdedos Fernando, Dussart Philippe, Mongkolsapaya Juthathip, Screaton Gavin R, Rey Félix A

Abstract excerpt

Dengue disease is caused by four different flavivirus serotypes, which infect 390 million people yearly with 25% symptomatic cases and for which no licensed vaccine is available. Recent phase III vaccine trials showed partial protection, and in particular no protection for dengue virus serotype 2 (refs 3, 4). Structural studies so far have characterized only epitopes recognized by serotype-specific human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25581790
DOI: 10.1038/nature14130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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