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Article

Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection.

Scientific reports - 12 Jan 2015

Darch Sophie E, McNally Alan, Harrison Freya, Corander Jukka, Barr Helen L, Paszkiewicz Konrad, Holden Stephen, Fogarty Andrew, Crusz Shanika A, Diggle Stephen P

Abstract excerpt

The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly resistant to multiple antibiotics. Here, we investigate the phenotypic and genotypic diversity of 44 morphologically identical P. aeruginosa isolates taken from a single CF patient sputum sample. Comprehensive phenotypic analysis of isolates...

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Share to Cystic Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25578031
DOI: 10.1038/srep07649
PMCID: PMC4289893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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