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Article

Pseudomonas aeruginosa population diversity and turnover in cystic fibrosis chronic infections.

American journal of respiratory and critical care medicine - 15 Jun 2011

Mowat Eilidh, Paterson Steve, Fothergill Joanne L, Wright Elli A, Ledson Martin J, Walshaw Martin J, Brockhurst Michael A, Winstanley Craig

Abstract excerpt

RATIONALE: Pseudomonas aeruginosa isolates from chronic cystic fibrosis lung infections display multiple phenotypes indicating extensive population diversity. OBJECTIVES: We aimed to examine how such diversity is distributed within and between patients, and to study the dynamics of single-strain phenotypic diversity in multiple patients through time. METHODS: Sets of 40 P. aeruginosa isolates per sputum samples...

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PMID: 21297072
DOI: 10.1164/rccm.201009-1430OC

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