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Article

Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis.

Scientific reports - 5 Jun 2015

Clark Shawn T, Diaz Caballero Julio, Cheang Mary, Coburn Bryan, Wang Pauline W, Donaldson Sylva L, Zhang Yu, Liu Mingyao, Keshavjee Shaf, Yau Yvonne C W, Waters Valerie J, Elizabeth Tullis D, Guttman David S, Hwang David M

Abstract excerpt

Chronic airway infections caused by Pseudomonas aeruginosa contribute to the progression of pulmonary disease in individuals with cystic fibrosis (CF). In the setting of CF, within-patient adaptation of a P. aeruginosa strain generates phenotypic diversity that can complicate microbiological analysis of patient samples. We investigated within- and between- sample diversity of 34 phenotypes among 235 P. aeruginosa...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26047320
DOI: 10.1038/srep10932
PMCID: PMC4456944

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