Article
Quantifying population genetic differentiation from next-generation sequencing data.
Genetics - 1 Nov 2013
Fumagalli Matteo, Vieira Filipe G, Korneliussen Thorfinn Sand, Linderoth Tyler, Huerta-Sánchez Emilia, Albrechtsen Anders, Nielsen Rasmus
Abstract excerpt
Over the past few years, new high-throughput DNA sequencing technologies have dramatically increased speed and reduced sequencing costs. However, the use of these sequencing technologies is often challenged by errors and biases associated with the bioinformatical methods used for analyzing the data. In particular, the use of naïve methods to identify polymorphic sites and infer genotypes can inflate downstream...
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