Article
Association between interleukin-1β and tumor necrosis factor-α polymorphisms and symptoms of dyspepsia.
Molecular medicine reports - 1 May 2015
Tahara Tomomitsu, Shibata Tomoyuki, Okubo Masaaki, Ishizuka Takamitsu, Kawamura Tomohiko, Yamashita Hiromi, Nakamura Masakatsu, Nakagawa Yoshihito, Nagasaka Mitsuo, Arisawa Tomiyasu, Ohmiya Naoki, Hirata Ichiro
Abstract excerpt
Interleukin (IL)‑1β, and tumor necrosis factor (TNF)‑α have significant roles in the mediation of inflammatory immune responses and are also potent inhibitors of gastric acid secretion in the stomach. The present study aimed to investigate the associations between polymorphisms at position ‑31 (T>C) of the IL‑1β gene and ‑857 (C>T) of the TNF‑α gene with dyspeptic symptoms. Polymorphisms at position ‑31 (T>C) of...
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