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Article

Isolation Housing Exacerbates Alzheimer's Disease-Like Pathophysiology in Aged APP/PS1 Mice

7 Jan 2015

Abstract excerpt

BACKGROUND: Alzheimer's disease is a neurodegenerative disease characterized by gradual declines in social, cognitive, and emotional functions, leading to a loss of expected social behavior. Social isolation has been shown to have adverse effects on individual development and growth as well as health and aging. Previous experiments have shown that social isolation causes an early onset of Alzheimer's disease-like...

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Alzheimer's disease research and treatments
Amyotrophic Lateral Sclerosis Research
Dementia and Cognitive Impairment Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25568286
DOI: 10.1093/ijnp/pyu116

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Isolation Housing Exacerbates Alzheimer's Disease-Like Pathophysiology in Aged APP/PS1 MicePMID 25568286Read ↗

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