Article
Influence of adding pyrroloquinoline quinone to parenteral nutrition on gut-associated lymphoid tissue.
JPEN. Journal of parenteral and enteral nutrition - 1 Sept 2011
Omata Jiro, Fukatsu Kazuhiko, Murakoshi Satoshi, Moriya Tomoyuki, Ueno Chikara, Maeshima Yoshinori, Okamoto Koichi, Saitoh Daizoh, Yamamoto Junji, Hase Kazuo
Abstract excerpt
BACKGROUND: Experimental intravenous (IV) parenteral nutrition (PN) diminishes gut-associated lymphoid tissue (GALT) cell number and function. PN solution cannot maintain GALT at the same level as a normal diet, even when delivered intragastrically (IG). Previous studies demonstrated pyrroloquinoline quinone (PQQ)-deficient mice to be less immunologically responsive. Because standard (STD) PN solution lacks PQQ,...
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