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Article

Development and validation of the JAX Cancer Treatment Profile™ for detection of clinically actionable mutations in solid tumors.

Experimental and molecular pathology - 1 Feb 2015

Ananda Guruprasad, Mockus Susan, Lundquist Micaela, Spotlow Vanessa, Simons Al, Mitchell Talia, Stafford Grace, Philip Vivek, Stearns Timothy, Srivastava Anuj, Barter Mary, Rowe Lucy, Malcolm Joan, Bult Carol, Karuturi Radha Krishna Murthy, Rasmussen Karen, Hinerfeld Douglas

Abstract excerpt

BACKGROUND: The continued development of targeted therapeutics for cancer treatment has required the concomitant development of more expansive methods for the molecular profiling of the patient's tumor. We describe the validation of the JAX Cancer Treatment Profile™ (JAX-CTP™), a next generation sequencing (NGS)-based molecular diagnostic assay that detects actionable mutations in solid tumors to inform the...

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Identifiers

PMID: 25562415
DOI: 10.1016/j.yexmp.2014.12.009
PMCID: PMC4481190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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