A solute carrier family 22 member 3 variant rs3088442 G→A associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory response.

doi:10.1074/jbc.M114.584953

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A solute carrier family 22 member 3 variant rs3088442 G→A associated with coronary heart disease inhibits lipopolysaccharide-induced inflammatory response.

The Journal of biological chemistry - 27 Feb 2015

Li Lu, He Meian, Zhou Li, Miao Xiaoping, Wu Fangqing, Huang Suli, Dai Xiayun, Wang Tian, Wu Tangchun

Abstract excerpt

Recent genome-wide association studies have identified single-nucleotide polymorphism (SNPs) within the SLC22A3 (solute carrier family 22 member 3) gene associated with coronary heart disease (CHD) in the Caucasian population. We performed molecular analysis to investigate the potential role of SLC22A3 variants in CHD. Our study showed that the common polymorphism rs3088442 G→A, which is localized in the 3' UTR...

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PMID: 25561729
DOI: 10.1074/jbc.M114.584953
PMCID: PMC4342451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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