Molecular Genetics of Thrombotic Myeloproliferative Neoplasms: Implications in Precision Oncology

Abstract excerpt

Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) include polycythaemia vera, essential thrombocythaemia, and primary myelofibrosis. Unlike monogenic disorders, a more complicated series of genetic mutations are believed to be responsible for MPN with various degrees of thromboembolic and bleeding complications. Thrombosis is one of the early manifestations in patients with MPN. To date, the driver...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Eosinophilic Disorders and Syndromes
• Share to Kruppel-like factors research
• Share to Myeloproliferative Neoplasms: Diagnosis and Treatment